Sexually transmitted infections (STIs) are a major public health concern. The United Kingdom (UK) has some of the most advanced STI surveillance systems globally. This review uses national surveillance data to describe remarkable changes in STI epidemiology in the UK over the last century and explores behavioural and demographic shifts that may explain these trends. The past ten years have seen considerable improvements in STI service provision and the introduction of national public health interventions. However, sexual health inequalities persist and men who have sex with men, young adults and black ethnic minorities remain a priority for interventions. Technological advances in testing and a shift in sexual health service commissioning arrangements will present both opportunities and challenges in future
