Green Chemistry and Biginelli Reaction

Abstract

Synthesis of some 5-acetyl-6-methyl-4-aryl-3,4-dihydropyrimidne-2-one, 5-acetyl-6-methyl-4-aryl-3,4- dihydropyrimidne-2-thione, 5-ethoxycarbonyl-6-methyl-4-aryl-3,4-dihydropyrimidine-2-one and 5- ethoxycarbonyl-6-methyl-4-aryl-3,4-dihydropyrimidine-2-thione by green chemistry methods without catalysis and without solvent, the reaction progress was followed by TLC analysis and the chemical structure confirmed by spectroscopic analysis (UV, IR an

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