Protective Effect of Quercetin Treatment on Gut Microbiota Imbalance in Obesity-Associated NAFLD in Patients and in HFD-FED Mice

Abstract

2 p.Gut microbiota is involved in obesity, metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). Quercetin may modulate the intestinal microbiota composition, suggesting therapeutic potential in NAFLD. The present study aims to establish the role of gut microbiota imbalance in obesity-related NAFLD development in patients and in an in vivo model and to investigate benefits of experimental treatment with quercetin. Resumen de un trabajo resultado del proyecto de investigación financiado por la Consejería de Educación de la Junta de Castilla y León (referencia LE063U16)S