The present work describes the biological activities using the marine sponges collected
from kanyakumari. The sponges are such as the Callyspongia diffusa, Echinodictyum
gorgonoides, Callyspongia reticutis, Gelliodes cellaria, and Thalysias vulpine. It is revealed that
the sponges showed the antifungal activity against the various fungal strains such as the
Aspergillus niger, Pencillium notatum,and Candida albicans by using the agar well diffusion
method. The sponge crude extracts seems to have effective cytotoxic property that was detected by
Brine shrimp assay. Hence it is assumed that the marine sponges act as the vital source for the
development of anticancer drugs