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Ventilator-associated Pneumonia: A Study of Patients admitted in Internal Intensive Care Unit of Ali Asghar Hospital, Shiraz

Abstract

Introduction: Ventilator-associated pneumonia is defined as a pneumonia occurring in patients within 48 hours or more after intubation with an endotracheal tube or tracheostomy tube and which not present before. The main objective of this study was to determine prevalence, predisposing factors and outcomes for ventilator associated pneumonia in an internal intensive care unit in a tertiary hospital. Material and Methods: In this retrospective review, all adult intensive care unit admitted patients at Ali Asghar Hospital with clinically and radiologically suspected ventilator-associated pneumonia between March 2009 and May 2010 were considered. The following data were recorded for each patient: demographic data, culture densities, chest radiological findings, pathogen(s), age, white blood cell count (WBC), presence of comorbid diseases, duration of hospital stay prior to diagnosis, and hospital survival. Data was assessed with SPSS software version 15 compatible for windows. Results: There were 49 patients in this study and most of the patients (69.3%) were males. Most of the patients (65.3%) were in more than 60 years age group of whom males were dominant. The most common risk factor was smoking, nasogastric tube, prolong duration of hospitalization, hospital admissions more than 2 times, prolong duration of intensive care unit admission, decreased level of consciousness and prolong ventilator support. The most common organism isolated was acinetobacter. Most of the patients were died (59.1%) of whom most were males. Discussion and conclusion: This study demonstrated that ventilator associated pneumonia is an important nosocomial infection among patients receiving mechanical ventilation in a community hospital and it is associated with greater hospital mortality rates and longer lengths of stay in the intensive care unit and hospital. Prevention is better than cure. Ventilator associated pneumonia is a well preventable disease and a proper approach decreases the hospital stay, cost, morbidity and mortality

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