The paper concerns both the numerical and experimental investigation of turbulent liquid oxygen/hydrogen spray combustion for elevated subcritical pressure and cryogenic inlet temperature conditions. In particular, the combustion in the single injector combustion chamber is studied where experimental data are obtained for gas phase temperature and both droplet size and velocities. The model uses an Eulerian--Lagrangian formulation for the gas and the liquid phase, respectively. Detailed models for droplet heating and vaporization in a convective flow field are employed, and detailed gas phase reactions are accounted for through use of a flamelet model for turbulent spray combustion. The results show a very good agreement between experimental and computational spray characteristics. The computed gas phase temperature lies somewhat above the experimental values which is associated with CARS single shot measurements and incomplete data for the initial conditions of the combustion process