Kellermann, Tracy

English

Cape Town University OpenUCT

A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.

Analysis of chemical and morphological variation in the Ramalina siliquosa species complex.

Antiinfective potential of natural products: how to develop a stronger in vitro ‘proof-of-concept’.

Antiinfective research and development – problems, challenges, and solutions.

Antimicrobials: time to act!

Attempted isolation and success in the culturing of a broad spectrum of lichen-forming and lichenicolous fungi.

Bioactive phenolic compounds from a medicinal lichen, Usnea longissima.

Biodiversity and drug discovery – a symbiotic relationship.

Botryorhodines A-D, antifungal and cytotoxic depsidones from Botryosphaeria rhodina, and endophyte of the medicinal plant Bidens pilosa.

Chemical and morphological evolution in Parmelia Sect. hypotrachyna: product of ancient hybridization?

Commentary: Challenges in using traditional systems of medicine.

Community-acquired Klebsiella pneumoniae complicated skin and soft-tissue infections of extremities: emphasis on cirrhotic patients and gas formation.

Comparitive mycobacterial genomics as a tool for drug target and antigen discovery.

Cytotoxic activity of compounds from the lichen Cladonia convoluta.

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.

Desiccation survival times in different desiccation-tolerant plants.

Determination of antioxidative potential of lichen Usnea ghattensis in vitro.

Development and characterization of an in vivo central venous catheter Candida albicans biofilm model.

Discovery new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens.

Drimane-type sesquiterpenoids as chemosystematic markers of Canellaceae.

Drug discovery from medicinal plants.

Emergence of KPCpossessing Klebsiella pneumoniae in

Experimental studies on the growth of usnic acid production in “lichen” Usnea ghattensis in vitro.

From the Zulu medicine to the European phytomedicine Umckaloabo ®.

Further studies on the antibiotic activity of lichens.

Highthroughput screen for detecting antimycobacterial agents.

HPLC-SPE-NMR characterization of University of Cape Town sesquiterpenoids in an antimycobacterial fraction of Warburgia salutaris.

In vivo fluconazole pharmacodynamics and resistance development in a previously susceptible Candida albicans population examined by microbiologic and transcriptional profiling.

Indigenous plant genetic resources of South Africa. Perspectives On New Crops and New Uses.

Influence of the cell wall on ciprofloxacin susceptibility in selected wildtype Gram-negative and Gram-positive bacteria.

Lessons on integration from the developing world’s experience.

Lichens – a promising source of bioactive secondary metabolites.

Molecular characterization and action of usnic acid: a drug that inhibits proliferation of mouse polyomavirus in vitro and whose main target is RNA transcription.

Natural products as a resource for new drugs.

Natural products in drug discovery and development.

New smallmolecule synthetic antimycobacterials.

Novel biaryl oxazolidinones: in vitro and in vivo activities with pharmacokinetics in an animal model.

Persistence of antibiotic resistant bacteria.

Pharmacokinetics-pharmacodynamics of antimicrobial therapy: it’s not just for mice anymore.

Plant products as antimicrobial agents.

Prevalence of extended spectrum ß-lactamase (ESBL)-producing clinical isolates in the Asia-Pacific region and University of Cape Town South Africa: regional results from SENTRY Antimicrobial Surveillance Program

Progress in functional genomics approaches to antifungal drug target discovery.

Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City.

Recent advances in the preclinical evaluation of the topical antibacterial agent REP8839. Current Opinion in

Rifapentine: A viewpoint.

South Africa to bring traditional healers into mainstream medicine.

Standards Institute, formerly NCCLS. M27-A2. Reference Method for Broth Dilution Antifungal Susceptibility Testing of Yeasts; Approved Standard-Second Edition.

Supplement to the ‘Chemical and botanical guide to lichen products’.

The ability of biological and organic synthetic materials to accumulate atmospheric particulates containing copper, lead, nickel and strontium.

The capsule of Mycobacterium tuberculosis and its implication for pathogenicity. Tubercle and Lung Disease

The molluscicidal activity of Apodytes dimidiate E. Meyer ex Arn (Icacinaceae), Gardenia thunbergia L.f. (Rubiaceae) and Warburgia salutaris (Bertol. F.) Chiov. (Cannelaceae), three South African plants.

The mycobacterial cell wall: structure, biosynthesis and sites of drug action.

The role of natural product chemistry in drug discovery.

The use of chemistry in the systematics of the lichens.

Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs.

Use of indigeneous and indigenised medicines to enhance personal well-being: a South African case study.

A Pharmacological investigations of South Africa Lichens, Dessication-tolerant Plants and Medicinal Tree, Warburgia Salutaris

https://open.uct.ac.za/bitstream/11427/3284/1/thesis_hsf_2010_kellermann_t.pdf

A Pharmacological investigations of South Africa Lichens, Dessication-tolerant Plants and Medicinal Tree, Warburgia Salutaris

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Cape Town University OpenUCT