This paper details the implementation process of an embedded structural health monitoring (SHM) system enabling condition-based maintenance of aircraft nacelles. One critical issue before being able to make use of such system is to ensure the effective bonding of the chosen actuators and sensors with their host structure, especially as the latter will be exposed to harsh environments and wide operational variability. In this work, we are concerned with the composite components of the nacelle and we use piezoelectric elements as both sensors and actuators. We propose an integrated approach that allows to validate a combination “Substrate—Glue—Piezoelectric” (SGP) and thus provides criteria to choose and size these assemblies. This validation scheme is based on the observation of the variations of the static capacity of the piezoelectric element after enduring various temperature and stress conditions when bonded to its host structure. Based on those SGP combinations, an active SHM strategy interrogating the structure by means of elastic wave propagation is currently being developed and preliminary results on samples representative of the nacelle are presented and discussed.Projet AIRCELLE (EPICE/CORALIE