The first case of poisoning of a dog with Furadan 35-ST in Serbia is
described. The active ingredient of Furadan 35-ST is carbofuran
(2,3-dihydro-2,2-dimethyl-7- benzofuranyl methyl carbamate), a carbamate
insecticide, acaricide and nematocide. This highly poisonous substance is
classified by the World Health Organisation into Class 1 b and in Serbia into
Group 1 of The List of Poisons. Pathological assessment revealed hyperaemia
and degenerative and necrotic changes in the liver, kidneys and heart. In
addition, lysis of the nuclei in the motor neurons, loss of tigroid substance
and pericellular oedema in the ventral horns of the spinal cord, and acute
pancreatitis were found. In addition to the non-specific changes (hyperaemia,
degenerative and necrotic changes in the parenchymal organs), the ones in the
ventral horns of the spinal cord and acute pancreatitis may lead to carbamate
poisoning being suspected. The diagnosis was established on the grounds of
toxicological-chemical conformation of carbofuran by means of GC-MS in
addition to the macroscopic, microscopic findings in tissue samples taken
from the stomach and the liver, which confirmed the suspicion of the dog
having been poisoned with the carbamate insecticide. In the current case the
results of the diagnostic procedures provided foundations for the initiation
of criminal proceedings
