The use of dietary additives is becoming a very interesting practise to improve animal health and performance in poultry production. Thepax® is a prebiotic that includes inactivated Saccharomyces cerevisiae Var. ellipsoideus cells and nutrients such as vitamins, enzymes, amino acids and short chain polypeptides. The effects of supplementing diet by Thepax® via potable water on growth and carcass yield were studied in broilers. Two treatments, an active with Thepax® and a control treatment, were used on 120 male and female chicks of the Hubbard JV breed. Birds were divided into 6 groups of 20 birds each managed on floor and received the same starter, grower and finisher concentrates based on maize and soybean meal during a 37 days trial period. Thepax®(0.5 ml of the additive for 1 litre of water) was used during only one month. Body weight and daily growth rate seemed to increase by 6.2% and 6.4%, respectively, in birds receiving Thepax® compared to control birds. Feed conversion ratio and water intake were similar (P≥0.201) for both groups of birds. The effect of the additive was important on birds’ health. The mortality rate decreased (P=0.0241) by around 71% in birds receiving Thepax®compared to that in control birds. Furthermore, the active group of birds deposited (P = 0.0172) less abdominal fat (-35.2%) without affecting carcass yield. Positive effects of Thepax® with its structure and composition may be an important additional source of nutrients supports growth and enhance feed ingredients digestibility and beneficial intestinal microflora activity in broilers. In conclusion, Thepax® administered to broilers in drinkable water may improve birds’ health and reduce abdominal fat without compromising carcass yield
