BackgroundCancer and its treatments significantly affect the quality of life (QoL) of patients. This remains understudied among Vietnamese women with cancer.ObjectivesThis study explored the QoL of Vietnamese women with cancer and identified key influencing factors.MethodIn 2022, this study analyzed 214 Vietnamese women with cancer from four hospitals, assessing pain levels (Visualized Pain Scale), functional capacity (Karnofsky Performance Status Scale), and QoL (SF12). Analyses used SPSS 26.0, including t-tests, ANOVA, and hierarchical linear regression models.ResultsSF12-PCS and SF12-MCS scores were 46.61 ± 9.70 and 46.96 ± 9.06. Pain score (β = −0.304, p β = −0.311, p β = 0.259, p β = −0.311, p r = −0.165, p = 0.016), number of symptoms (r = −0.220, p = 0.001), and pain (r = −0.444, p r = −0.156, p = 0.036) and the number of symptoms (r = −0.362, p r = 0.222, p = 0.001) and (r = 0.281, p ConclusionCulturally sensitive care, pain management, and tailored support programs addressing physical, psychological, spiritual, and social aspects can enhance QoL for these women.</jats:sec
