Eucalyptus urophylla (ampupu) is one of the most commonly cultivated species in Brazil for industrial scale particleboard production. This study investigates the reuse of Eucalyptus urophylla sawmill waste as a raw material for particleboard manufacturing, addressing the growing need for sustainable material solutions. Without prior particle homogenization, two manufacturing approaches were tested: single-layer and three-layer boards. Using a castor-oil-based polyurethane resin (10 % for single-layer and 12 % for three-layer boards), the panels were pressed at 5 MPa for 10 minutes at 100 °C. Performance evaluation under standards revealed that multilayer panels demonstrated superior mechanical and physical properties, while single-layer boards did not meet classification standards, highlighting the benefits of optimizing wood waste in multilayer compositions