Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic, debilitating inflammatory skin disease defined by the occurrence of painful inflamed nodules, abscesses, sinus tracts, and fistulas. Patients frequently present with several comorbidities nonetheless, the topic is still often neglected. Here, this study reports the first case of Mondor’s disease (MD) in a patient with recently diagnosed hidradenitis suppurativa. A 52-year-old Caucasian man presented with nodules, scarring and fistulas primarily affecting the anogenital area and right thigh, diagnosed 3 months earlier as HS. Moreover, the physical examination revealed multiple lipomas in the trunk area and a palpable subcutaneous 10 cm cord-like structure along the anterolateral wall of the thorax on the right side that appeared 2 weeks before the admission. The patient did not have a history of trauma, infection, malignancy, previous thromboembolic events, excessive training, or any procedure. Laboratory tests performed revealed increased CRP, D-dimer, and haematocrit levels. A thrombosed hypoechoic superficial vein with no Doppler flow was observed during the ultrasound examination of the affected area. Regarding the anamnesis and the clinical picture, a diagnosis of Mondor’s disease was made. Mondor’s disease is a rare condition that resolves spontaneously in four to eight weeks however, it is often underdiagnosed owing to a lack of awareness