Modelling the burden caused by gene expression: an in silico
investigation into the interactions between synthetic gene circuits and their
chassis cell
In this paper we motivate and develop a model of gene expression for the
purpose of studying the interaction between synthetic gene circuits and the
chassis cell within which they are in- serted. This model focuses on the
translational aspect of gene expression as this is where the literature
suggests the crucial interaction between gene expression and shared resources
lies