We introduce kernel nonparametric tests for Lancaster three-variable
interaction and for total independence, using embeddings of signed measures
into a reproducing kernel Hilbert space. The resulting test statistics are
straightforward to compute, and are used in powerful interaction tests, which
are consistent against all alternatives for a large family of reproducing
kernels. We show the Lancaster test to be sensitive to cases where two
independent causes individually have weak influence on a third dependent
variable, but their combined effect has a strong influence. This makes the
Lancaster test especially suited to finding structure in directed graphical
models, where it outperforms competing nonparametric tests in detecting such
V-structures