[症例報告]Colonic cancer associated with radiation colitis : A case report and a brief review of the literature

Abstract

A 62-year-old Japanese woman was admitted to our hospital because of a slight rectal bleeding and stenosis in the left colon on a barium study. The patient had undergone a total hysterectomy and received radiotherapy for uterine cervical cancer at 35 years of age. Twenty-seven years after the treatment of uterine cervical cancer, the patient presented with slight rectal bleeding. The physical examination revealed a mid-line surgical scar, brown pigmentation of the skin and wall thickness in the lower abdomen consistent with radiation effect. A barium enema study showed stenosis of the descending colon. Colonoscopy was failed because of difficulty in inserting the endoscope. The patient underwent a left colectomy with lymph node dissection. The lower abdominal cavity showed extensive fibrosis (so-called frozen pelvis) which is often associated with the radiation effect. The resected colon showed a macroscopic Type 2 tumor which invaded the retroperitoneal space and the tumor was histologically diagnosed to be well-differentiated adenocarcinoma (stage IV). Severe endoarteritis was also observed in the vicinity of the tumor. The patient is doing well at the time of writing.論文http://purl.org/coar/resource_type/c_650

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