The Genomic Data Mine

Abstract

The genomic data mine represents a fundamental shift from genetics to genomics, essentially from the study of one gene at a time to the study of entire genetic metabolic networks and whole genomes. Experimental laboratory data are deposited into large public repositories and a wealth of computational data mining algorithms and tools are applied to mine the data. The integration of different types of data in the genomic data mine will contribute towards an understanding of the systems biology of living organisms, contributing to improved diagnoses and individualized medicine. This chapter focuses on the genomic data mine consisting of text data, map data, sequence data, and expression data, and concludes with a case study of the Gene Expression Omnibus (GEO). Keywords genomics; text mining; data mining; gene expression data “ … Medical schools, slow to recognize the profound implications of genomics for clinical medicine, have been lurching, if not stumbling, forward to embrace the genomification of medicine…