Practical Image Restoration of Thick Biological Specimens Using Multiple

Abstract

this paper we present a quantitative analysis of the application of the Schiske formalism to the imaging of thick biological specimens. We use a complete exit wave reconstruction based on 40 images as a standard for comparison. In addition, based on our experiments on the mechanism of image formation for thick sections, we propose a new way to combine the amplitude and phase contrast components to generate the restored image. This approach better accounts for the contribution of multiple scattering at low resolutio