Fusion of autoradiographies with an MR volume using 2-D and 3-D linear transformations

Abstract

In the past years, the development of 3-D medical imaging devices has given access to the 3-D imaging of in vivo tissues, from an anatomical (MR, CT) or even functional point of view (fMRI, PET, SPECT). However, despite huge technological progress, the resolution of these images is still not suffiient to image to anatomical or functional details, that can only be revealed by in vitro imaging (e.g. histology, autoradiography), eventually enhanced by staining. The deep motivation of this work is the comparison of activations detected..