Buruli ulcer is a disease of skin and soft tissue caused by Mycobacterium ulcerans. It can leave affected people scarred and disabled. What are the prospects for disease control

Aiga

Amofah

Aujoulat

Bayley

Clancey

Cole

Daniel

Debacker

Dega

Drummond

Evans

Francoise Portaels

George

Gerd Pluschke

Gooding

Hayman

Huygen

Jenkin

John A Hayman

Johnson

Kingsley Asiedu

Kris Huygen

MacCallum

Marsollier

Marston

Meyers

Oluwasanmi

Pamela L. C Small

Paul D. R Johnson

Portaels

Prevot

Richard W Merritt

Ross

Siegmund

Smith

Stienstra

Stinear

Teelken

Timothy Stinear

Veitch

PLoS Medicine

English

PubMed

Buruli ulcer is now emerging from long years of neglect: interest and momentum are growing. However, there is much to do if we are to understand why the disease is becoming more common and how this relates to human activity. The current control strategy of early detection and treatment should be scaled up in the affected countries. Our ultimate goal is the development of an effective and safe vaccine able to provide long-lasting protection for those who live in endemic areas

Johnson, P. D. R.

Stinear, T.

Small, P. L. C.

Pluschke, G.

Merritt, R. W.

Portaels, F.

Huygen, K.

Hayman, J. A.

Asiedu, K.

Tropmed Central Antwerp

Buruli ulcer (M. ulcerans infection): new insights, new hope for disease control

Johnson Paul D. R

Stinear Timothy

Small Pamela L. C

Pluschke Gerd

Merritt Richard W

Portaels Francoise

Huygen Kris

Hayman John A

Asiedu Kingsley

Public Library of Science (PLOS)

 Infection): New Insights, New Hope for Disease Control

Paul D R Johnson

Pamela L C Small

Directory of Open Access Journals

Buruli ulcer (M. ulcerans infection): new insights, new hope for disease control.

Johnson, PDR

Stinear, T

Small, PLC

Plushke, G

Merritt, RW

Portaels, F

Huygen, K

Hayman, JA

Asiedu, K

University of Melbourne Institutional Repository

Buruli ulcer (M. ulcerans infection): New insights, new hope for disease control

Crossref

Buruli Ulcer (M. ulcerans Infection): New Insights, New Hope for Disease Control

A large localized outbreak of Mycobacterium ulcerans infection on a temperate southern Australian island.

A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells.

A new mycobacterial infection in man.

Acquired T-helper 1 lymphocyte anergy following infection with Mycobacterium ulcerans.

Acute, oedematous Mycobacterium ulcerans infection in a farmer from far north Queensland.

An outreach education and treatment project in Ghana for the early stage of Mycobacterium ulcerans disease.

Analysis of Mycobacterium species for the presence of a macrolide toxin, mycolactone.

Aquatic insects as a vector for Mycobacterium ulcerans.

Aquatic snails, passive hosts of Mycobacterium ulcerans.

Assessing water-related risk factors for Buruli ulcer: A case-control study in Ghana.

Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice.

Bactericidal activity of riframpicin and streptomycin treatment for early huyman M. ulcerans lesions.

BCG vaccination against Mycobacterium ulcerans infection (Buruli ulcer). First results of a trial in Uganda.

Beliefs and attitudes toward Buruli ulcer in Ghana.

Buruli ulcer in Ghana: Results of a national case search.

Buruli ulcer in Ghana.

Buruli ulcer: Differences in treatment outcome between two centres in Ghana.

Cytokine proﬁ les of patients infected with Mycobacterium ulcerans and unaffected household contacts.

Detection of Mycobacterium ulcerans in environmental samples during an outbreak of ulcerative disease.

Development of a PCR assay for rapid diagnosis of Mycobacterium ulcerans infection.

Differential production of systemic and intralesional gamma interferon and interleukin-10 in nodular and ulcerative forms of Buruli disease.

Dryreagent-based PCR as a novel tool for laboratory conﬁ rmation of clinically diagnosed Mycobacterium ulcerans-associated disease in areas in the tropics where M. ulcerans is endemic.

Ecology and transmission of Mycobacterium ulcerans.

editors (2000) Buruli ulcer: Mycobacterium ulcerans infection. Geneva: World Health Organization. Available: http:⁄⁄www.who.int/gtb-buruli/publications/PDF/Buruli_ulcer_ monograph.PDF.

Emergence of Buruli ulcer disease in the Daloa region of Côte d’Ivoire.

Epidemiologic observations on cases of Buruli ulcer seen in a hospital in the Lower Congo.

Epidemiology of Mycobacterium ulcerans infection (Buruli ulcer) at Kinyara,

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.

Identiﬁ cation of Mycobacterium ulcerans in the environment from regions in Southeast Australia in which it is endemic with sequence capture-PCR.

Insects in the transmission of Mycobacterium ulcerans infection.

McQueen A

Microbiology. TB—A new target, a new drug.

Mycobacterial infections of the skin.

Mycobacterium bovis BCG vaccination as prophylaxis against Mycobacterium ulcerans osteomyelitis in Buruli ulcer disease.

Mycobacterium ulcerans (Buruli) skin ulceration in Nigeria.

Mycobacterium ulcerans disease (Buruli ulcer) in rural hospital,

Mycobacterium ulcerans infection (Buruli ulcer): First reported patients in Togo.

Mycobacterium ulcerans infection in a child from Angola: Diagnosis by direct detection and culture.

Mycobacterium ulcerans treatment costs,

Mycolactone: A polyketide toxin from Mycobacterium ulcerans required for virulence.

Organization

Postulated epidemiology of Mycobacterium ulcerans infection.

Prospects for vaccine development against Buruli disease.

Psychosocial aspects of health seeking behaviours of patients with Buruli ulcer in southern Benin.

Study of a mycobacterium causing skin ulceration in Uganda.

The emergence of Mycobacterium ulcerans infection near Melbourne.

The protective effect of BCG against Mycobacterium ulcerans disease: A controlled trial in an endemic area of Uganda.

World Health Organization

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1087202

Buruli Ulcer (M. ulcerans Infection): New Insights, New Hope for Disease Control

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Tropmed Central Antwerp

Public Library of Science (PLOS)

Directory of Open Access Journals

Public Library of Science (PLOS)

University of Melbourne Institutional Repository

Crossref