Alobid, Isam

Calvo-Henriquez C

Langdon Montero, Cristobal

López Chacón, Mauricio

Marin C

Mullol i Miret, Joaquim

Rojas Lechuga, María Jesús

Viveros-Díez P

English

Background and objectives: The diagnostic criteria of chronic rhinosinusitis with nasal polyps (CRSwNP) include olfactory dysfunction. We hypothesize that patients with CRSwNP can self-assess their sense of smell better using a visual analog scale (VAS) than using smell tests.

Methods: A controlled cross-sectional study was performed. Adults diagnosed with severe CRSwNP waiting for endoscopic sinus surgery were included. A cohort of healthy controls was also studied. All participants completed the Barcelona Smell Test 24 (BAST-24), the 22-item Sinonasal Outcomes Test 22 (SNOT-22), and a VAS for loss of smell. Patients with CRSwNP underwent blood testing (eosinophil count, total serum IgE), computed tomography (Lund-Mackay Score), and nasal endoscopy.

Results: The study population comprised 138 patients with severe CRSwNP and 40 controls. The BAST-24 identification score was strongly correlated with the VAS score in the CRSwNP group (p=-0.79, P<.001) but not in the control group (p=-0.14; P=.39), this difference between groups being statistically significant (P<.001). A significant correlation was found between SNOT-22 item 21 (loss of smell) and BAST-24 identification (p=-0.65, P<.001), this difference being statistically significant (Z=-2.43; P=.015). The area under the receiver operating curve was 0.85, with 72.5% sensitivity and 93.1% specificity.

Conclusion: This study demonstrates a potential role of the VAS score for the screening of olfactory dysfunction in severe CRSwNP in daily clinical practice

Calvo Henriquez, C.

Viveros Díez, P.

Marin, C.

Diposit Digital de la Universitat de Barcelona

Journal of Investigational Allergology and Clinical Immunology

Validation of Visual Analogue Scale for loss of smell as a quick test in chronic rhinosinusitis with nasal polyps

https://diposit.ub.edu/dspace/bitstream/2445/216914/1/Validation%20of%20Visual%20Analogue%20Scale%20for%20loss%20of%20smell%20as%20a%20quick%20test%20in%20chronic%20rhinosinusitis%20with%20nasal%20polyps.pdf

Validation of Visual Analogue Scale for loss of smell as a quick test in chronic rhinosinusitis with nasal polyps

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Diposit Digital de la Universitat de Barcelona