Reverse Phase Thin Layer Chromatography of Aminoalkanethiosulfuric
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Abstract
Abstract: The experimental Rm values for a series of aminoalkanethiosulfuric acids, mercaptoalkanamines and aminoalkyl disulfides were determined by reverse phase thin layer chromatography. The Rm values were determined for various concentrations of methanol:water and the correlation obtained was extrapolated to 100 % water. These values permitted the calculation of the log P values for each substance. The log P values obtained by this method were compared with those obtained using the shake-flask method and by theoretical calculations utilizing fragment constants