A spannning subgraph F of G is a {K2,Cn}-factor if each component
of F is either K2 or Cn. A graph G is called a
({K2,Cn},n)-factor critical avoidable graph if G−X−e has a
{K2,Cn}-factor for any S⊆V(G) with ∣X∣=n and e∈E(G−X).
In this paper, we first obtain a sufficient condition with regard to isolated
toughness of a graph G such that G is {K2,Cn}-factor critical
avoidable. In addition, we give a sufficient condition with regard to tight
toughness and isolated toughness of a graph G such that G is
{K2,C2i+1∣i⩾2}-factor critical avoidable respectively