CORE
🇺🇦
make metadata, not war
Services
Services overview
Explore all CORE services
Access to raw data
API
Dataset
FastSync
Content discovery
Recommender
Discovery
OAI identifiers
OAI Resolver
Managing content
Dashboard
Bespoke contracts
Consultancy services
Support us
Support us
Membership
Sponsorship
Community governance
Advisory Board
Board of supporters
Research network
About
About us
Our mission
Team
Blog
FAQs
Contact us
research
A graphene field-effect transistor as a molecule-specific probe of DNA nucleobases
Authors
J Cervenka
N Dontschuk
+8 more
MT Edmonds
CI Pakes
S Prawer
KJ Rietwyk
A Schenk
O Shimoni
A Stacey
A Tadich
Publication date
1 March 2015
Publisher
'Springer Science and Business Media LLC'
Doi
Cite
Abstract
© 2015 Macmillan Publishers Limited. All rights reserved. Fast and reliable DNA sequencing is a long-standing target in biomedical research. Recent advances in graphene-based electrical sensors have demonstrated their unprecedented sensitivity to adsorbed molecules, which holds great promise for label-free DNA sequencing technology. To date, the proposed sequencing approaches rely on the ability of graphene electric devices to probe molecular-specific interactions with a graphene surface. Here we experimentally demonstrate the use of graphene field-effect transistors (GFETs) as probes of the presence of a layer of individual DNA nucleobases adsorbed on the graphene surface. We show that GFETs are able to measure distinct coverage-dependent conductance signatures upon adsorption of the four different DNA nucleobases; a result that can be attributed to the formation of an interface dipole field. Comparison between experimental GFET results and synchrotron-based material analysis allowed prediction of the ultimate device sensitivity, and assessment of the feasibility of single nucleobase sensing with graphene
Similar works
Full text
Open in the Core reader
Download PDF
Available Versions
RMIT Research Repository
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:researchbank.rmit.edu.au:r...
Last time updated on 13/05/2020
OPUS - University of Technology Sydney
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:opus.lib.uts.edu.au:10453/...
Last time updated on 13/02/2017
University of Melbourne Institutional Repository
See this paper in CORE
Go to the repository landing page
Download from data provider
oai:jupiter.its.unimelb.edu.au...
Last time updated on 06/01/2019