To the editors: Peanut remains the number one cause of death due to food-related anaphylaxis. Co-factors (e.g., febrile illness, vigorous exercise) that modify the severity of food allergic reaction are known to increase intestinal epithelial cell (IEC) barrier permeability, and patients with peanut allergy have higher serum levels of a major peanut allergen (Ara h 6) after peanut ingestion. Yet, we do not understand basic interactions between peanut and IECs
