Investigating the Molecular Function of Mutated Arabidopsis AS2 Gene

Abstract

This study aims to more deeply understand the role of the ASYMMETRIC LEAVES 2 (AS2) gene in Arabidopsis. During leaf development, the AS2 protein keeps the KNOX genes turned off so that leaves can develop. We use CRISPR technology to create mutations in specific regions of AS2. These mutations are predicted to change the protein structure of AS2, which may result in a mutated leaf. The analysis of the mutation allows us to better understand how AS2 keeps the KNOX genes off

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