Introduction: There is limited data about sex differences in patients undergoing a thoracic endovascular aortic repair (TEVAR) procedure. This study sought to examine the national inpatient sample (NIS) database to describe in-hospital outcomes by gender.
Methods: The NIS was searched for hospitalizations of adult patients who underwent TEVAR in 2019 and 2020. For this cohort, female patients were identified, and pregnant patients were excluded. The primary outcome was inpatient mortality. Secondary outcomes included hospital length of stay (LOS), and total hospital charges (TOTHCG).
Results: This study included 696 patients who underwent TEVAR. 255 (36.6%) females were identified, of which, 7 were pregnant and excluded from the study. Female patients who underwent TEVAR had higher prevalence of obesity (30.6% vs. 24.3%, p \u3c0.001), smoking (28.1% vs. 22.3%, p \u3c0.001), and CKD (5.2% vs. 4.2%, p \u3c0.001). In-hospital mortality was higher among the female cohort (6.1% vs. 4.0%, p \u3c 0.001). On multivariable regression, females who underwent TEVAR were associated with higher odds of inpatient mortality (OR 1.210, 95% CI 1.091-1.342, p \u3c0.001). Additionally, patients who underwent TEVAR and had ventricular arrythmias pay significantly more TOTHCG (600,004vs.462,216, P\u3c0.001) with longer LOS (23.5days vs. 15.7days, p \u3c0.001). On secondary analysis it has shown patients with ventricular arrhythmias who underwent TEVAR had higher odds of having acute kidney injury, developing shock, arrhythmias and congestive heart failure exacerbation.
Conclusion: In this nationally representative population‐based retrospective cohort study, female patients were associated with higher mortality and worse outcomes among patients undergoing TEVAR procedure
