Choroid segmentation in non-EDI OCT images of multiple sclerosis patients

Abstract

[Abstract]: Optical coherence tomography (OCT) is a non-invasive diagnostic technique that can image ocular structures. Recently, this imaging technique has been used to diagnose and monitor patients with multiple sclerosis (MS), as several clinical studies have linked the development of MS to various changes in the eye. Among the different structures, one of the relevant biomarkers for MS analysis is the choroid. Systems such as Enhanced Depth Imaging (EDI) provide detailed images of the choroid region. However, OCT images are not routinely captured using this technology unless the study is specifically focused on choroidal analysis. In this work we propose a robust approach, based on convolutional neural networks to segment the choroid in non-EDI OCT images. The results obtained show that the proposed network manages to delimit the inferior contour of the choroid in a similar way to the experts.Xunta de Galicia; ED431C 2020/24Xunta de Galicia; IN845D 2020/38Xunta de Galicia; ED431G 2019/01This research was funded by Instituto de Salud Carlos III, Government of Spain, DTS18/00136 research project; Ministerio de Ciencia e Innovación y Universidades, Government of Spain, RTI2018-095894-B-I00 research project; Ministerio de Ciencia e Innovaciónn, Government of Spain through the research project with reference PID2019-108435RB-I00; Consellería de Cultura, Educación e Universidade, Xunta de Galicia, Grupos de Referencia Competitiva, grant ref. ED431C 2020/24; Axencia Galega de Innovación (GAIN), Xunta de Galicia, grant ref. IN845D 2020/38; CITIC, Centro de Investigación de Galicia ref. ED431G 2019/01, receives financial support from Consellería de Educación, Universidade e Formación Profesional, Xunta de Galicia, through the ERDF (80%) and Secretaría Xeral de Universidades (20%). Emilio López Varela acknowledges its support under FPI Grant Program through PID2019-108435RB-I00 project

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