Introduction: Tongue is the first functioning organ in the embryonic era. Its developmental alterations can result in malfunctions with damage in distant districts. Craniocervical anatomy suggests that tongue dysfunction may be involved in the damage to the arteriovenous encephalic flow. Objective: To evaluate the possible relationship between short frenulum and cerebral vasal problems. Method: We conducted an epidemiological research comparing the presence of vascular problems in families where the visited subject had short frenulum (which is a genetically transmitted pathology) and families where the visited subject did not have abnormality of the frenulum. Results: The presence of short tongue frenulum was correlated with the presence of episodes of vascular damage in about 80% of cases, while in families not affected by this tongue alteration the percentage of damage was between 10 and 13%. Conclusions: The enormous influence that the presence of an altered tongue frenulum seems to have on the future possibility of developing vascular problems should induce a more careful assessment of the presence of an incorrect-sized frenulum