The article seeks to provide a comprehensive analysis of the cultural interactions that took place between Uzbekistan and Afghanistan in the 20th century. The study will examine the pivotal elements and significant events that influenced their strong bond and facilitated its expansion. These bonds have been reinforced via reciprocal esteem, common traditions, and a shared history. In the 20th century, the relationship between Afghanistan and Uzbekistan underwent a transformation, entering a new phase marked by increased collaboration and cross-cultural exchange. Additionally, it aims to furnish readers with information regarding the pivotal and sophisticated phases of their relationship's progression during the designated timeframe, while also serving as a valuable resource for individuals seeking to explore this subject in greater depth. The aim of this study is to analyze the key components and occurrences that have significantly contributed to the formation of a robust and mutually advantageous relationship between the involved parties. The Afghans and the people of Transoxiana have historically maintained significant and continuous cultural and social connections. Our relationship with Uzbekistan, a nation that safeguards the historic Transoxiana culture, has transitioned into a new era in the twentieth century
