Aspirin Therapy In Neurological Disorder Such As Migraine And Alzhemeirs Disease

Abstract

Aspirin, a widely used nonsteroidal anti-inflammatory medication, has a long history of therapeutic applications in pain relief, fever reduction, and inflammation management. Recent research has expanded its potential utility in treating neurological conditions such as migraines and Alzheimer's disease. For migraine management, aspirin's mechanism of action involves the suppressing the production of prostaglandins, a key factor in migraine-related inflammation and pain. Clinical trials have demonstrated its effectiveness in reducing the intensity and frequency of migraine attacks. Aspirin, especially when combined with metoclopramide, has proven to be a valuable treatment option for acute migraine episodes. In the case of Alzheimer's disease, which exhibits neurodegeneration, aspirin's anti-inflammatory and antioxidant properties have generated interest in its potential as a preventive and therapeutic agent. While epidemiological studies and biological processes have suggested aspirin's potential benefits, randomized studies have raised concerns about the risks of bleeding, outweighing the potential advantages. This review article examines the latest research on aspirin's role in managing and preventing migraines and Alzheimer's disease. It also discusses the clinical research regarding aspirin's effectiveness, safety profile, and possible side effects in these neurological conditions. Finally, the article explores the directions for future research involving aspirin in relation to migraines and Alzheimer's disease