In a study conducted in Singapore, a country prone to dengue outbreaks due to
its climate and urban population, researchers examined the effectiveness of
releasing male Aedes aegypti mosquitoes infected with Wolbachia (wAlbB strain)
to reduce dengue transmission. These infected males, when mating with wild-type
females, produced non-viable eggs, leading to vector suppression. Extensive
field trials involving over 600,000 residents in four townships were conducted
from 2018 to 2022. The results showed a 57% decline in total dengue incidence
and a 64% decline in clustered dengue incidence. This approach offers promise
for large-scale dengue control in regions facing rising dengue cases, providing
a critical solution in combating the disease