Data to accompany "Ventricular Intramyocardial Navigation for Tachycardia Ablation Guided by Electrograms (VINTAGE): Deep Ablation in Inaccessible Targets" pending publication in JACC: Clinical Electrophysiology, 2024

Abstract

Brief abstract of manuscript:Deep intramural myocardial targets for ventricular tachycardia (VT) are difficult to access, map, and ablate, resulting in high recurrence rates. We introduce a novel approach (VINTAGE) to access and ablate anatomically-challenging VT from within the myocardium. Yorkshire swine underwent intramyocardial navigation using guidewire/microcatheter combinations. Ablative guidewires were introduced from the right ventricular septal endocardium, steered into, and energized within intramyocardial targets traditionally considered inaccessible from the endocardium and epicardium, including LV summit, septum, and papillary muscles. Intramyocardial saline irrigation was important for RF ablation efficacy. VINTAGE was safe and efficacious at creating reproducible large intramural lesions.Attached is the spreadsheet containing raw data reported in the paper</p