Evaluating Bone Fracture Healing Utilizing Novel Ultrasound Modes, X-Ray and Dual-Energy X-Ray Absorptiometry in a Rabbit Model

Abstract

Background and Purpose Healing in bone fractures is a complex process involving local inflammation, angiogenesis (i.e., the creation of new blood vessels), and formation of a bone-building callus, all of which leads to returning the bone nearly to its pre-fracture state. This is the process in a bone where the fracture is clean and the fractured ends oppose each other. Five to 10 percent of fractures are described as non-union, which can lead to poor healing and long-term complications. The purpose of this study was to compare fracture healing in a rabbit model using x-ray, the traditional method for evaluating fracture healing, with ultrasound methods including color Doppler imaging (CDI) and power Doppler imaging (PDI), shear wave elastography (SWE), superb microvascular imaging (SMI), and Dual-Energy X-Ray Absorptiometry (DXA).https://jdc.jefferson.edu/radiologyposters/1012/thumbnail.jp

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