GBF Gesellschaft für Biotechnologische Forschung mbH, Braunschweig
Abstract
During the evolution process most cells have learned to use oxygen for
establishing higher functional regulations. For this purpose different
proteins have been developed which are able to react with oxygen; as
for instance hemoglobin and myoglobin for oxygen transport and storage
or cytochromes, which act in the respiratory chain as electron carriers
to reduce oxygen to water for generating energy. Also other proteins
are known, like oxidases, which are involved in the reduction of
oxygen. The question was therefore addressed, whether monitoring of
the activity of these proteins in dependence on the oxygen partial
pressure can be used to construct a biosensor for oxygen