The project CliCCHE (Climate change, Cities, Communities and Equity in Health), reflects the horizontal priority “Environment and fight against climate change” (i) by constructing an educational toolkit intertwining knowledge from different disciplines, (ii) by testing specific training courses and involving public administrations and local communities that will increase their knowledge and awareness about climate change and its impacts, in particular, on human health in urban contexts, (iii) by identifying the needs for an environmental and human health-oriented urban regeneration and (iv) by enabling citizens to co-designing their neighborhoods. The 2° Transnational Meeting took place in Ascoli Piceno, in November 2022. It focuses on checking the preparation of the educational toolkit (R3) and testing it in local workshops