Analisi di un campione di popolazione generale affetta da asma bronchiale e relazione con l’attività lavorativa

Abstract

. To find the impact of occupational exposure to irritants or sensitizers on the occurrence, recurrence and worsening of asthma and to identify unrecognized cases of occupational asthma in a general asthma clinic population sample, we studied 768 subjects (age: 16-46 yrs) with a diagnosis of asthma and a current or previous occupational activity. A trained survey worker administered a computer assisted interview in order to collect data on their demographic characteristics, smoking history, asthma severity, treatment, work history and current work status. Current or previous work did not appear to affect the severity of asthma, though more activtiy limitations were observed among subjects with current work (p=0.02). Overall, subjects who reported symptoms from Work Related Asthma (WRA), when compared to subjects without WRA, more frequently (p<0.05) reported having more severe symptoms, assuming antiasthmatic therapy, and having changed their job because of their asthma. With regard to their occupational history, subjects with WRA were more likely to work, or having worked in the past, in jobs at higher risk of exposure to occupational risk factors (sector, p=0.05; job title, p=0.001, respectively). Our findings suggest that additional studies are needed to detect factors that may hinder the recognition of WR

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