According to the Dutch chemist Gerrit Jan Mulder (1802–1880), the principal aim of university education was character building and moral edification. Professional training was of secondary importance. Mulder’s ideas about the vocation and moral mission of the university professor can serve as a historical counterpart to later Weberian, Mertonian, and contemporary ideas on the ethos of science. I argue that a revaluation of the moral precepts that Mulder saw as defining the life of an academic is helpful in dealing with the problems of late modern science, such as the replication crisis and research misconduct. Addressing such problems must start in the university classrooms. To empower students to internalize the principles of responsible conduct of research, we need an updated version of Mulder’s idea of the university professor as a moral agent