This dataset supports the study on the investigation of urban form design parameters and their relationship to outdoor thermal comfort and energy consumption in Cairo, Egypt. The study utilises Grasshopper for Rhino3D to manage parametric combinations of the urban geometry (Documentation video "Typologies") as such it uses the Ladybug-tools plugins which link Grasshopper with EnergyPlus for energy simulations (Documentation video "Simulation"). The CSV data file includes the input geometrical parameters (prefixed "IN:") and the corresponding output thermal comfort and energy use (prefixed "OUT:")