Background: Burns are injuries due to heat from fire or other hot objects that cause damage to the skin, the level of tissue damage depends on the type and length of exposure to heat sources. Increased ROS occurs after burns injury begins and can interfere with wound healing if it is too high in number. Definitive management is needed to accelerate the healing of burns. Honey and green tea (Camellia sinensis) are natural ingredients that contain anti -inflammatory and antioxidants that can reduce levels of ROS so that healing can be faster. Purposes: This research was conducted to see the effect of the combination of honey and green tea on healing the second degree of burns in white rats. Method: This type of research is experimental with the Post-test Only Control Design with the calculation of the area of the second degree burns on the 14th day after being given topical therapy combination of honey and green tea extract with a mixture composition (1 ml of honey: 1 ml of green tea extract: 1 ml of honey: 0.5 ml of green tea extract: and 0.5 ml of honey: 1 ml of green tea extract). Results: One way Anova statistical test analysis shows the value of P = 0.593 and Linear Regression analysis revealed a 7.9% effect of the combination of honey and green tea on the healing of second degree burns. Conclusion: The combination of honey and green tea has no significant effect on healing the second degree of burns in white rats
