Large-scale transformation processes initiated in the global and national economy by various drivers, including modern achievements of scientific and technical progress, primarily in the field of ICT and artificial intelligence, put forward new requirements for the methodology of strategic planning at all levels of its organizational structure. The focus of CEMI RAS researchers is on theoretical problems and practical experience of strategic planning at the micro- and mesoeconomic level, as well as new approaches and methods for modeling, forecasting and organizing business processes at domestic enterprises. Particular attention is paid to issues of assessing and improving the efficiency of their activities, analyzing the reasons that hinder the development of production and R&D, and finding ways to solve emerging problems. The problems of artificial intelligence in the social and humanitarian space are being actively studied. All of the above problems and ways to solve them are considered by the scientific community through the prism and in the context of radical changes in the global economic, technological and geopolitical landscape, high turbulence and uncertainty in economic development, increasing sanctions pressure from a number of powerful countries in the struggle for resources and political leadership, international and internal conflicts . Close attention is paid to the development and strengthening of the role of the national innovation ecosystem, the need for a multiple increase in government funding for the early stages of fundamental and applied research. Only a combination of targeted deregulation of industry priorities, primarily government, as well as corporate investments in science, technology, engineering and mathematics, education and human capital development, can strengthen the innovation base of the economy, ensure prosperity, economic and national security of the country. It is especially emphasized that in the strategic plan, priority should be given to system solutions that have scalability potential both in economic space and in economic time