Clinical management of compartment syndrome secondary to snakebite envenoming: a global scoping review

Abstract

A scoping review of international literature will be conducted to investigate challenges and treatment strategies for compartment syndrome following snakebite envenoming. To this end, case reports will be searched to characterise treatment challenges on a patient level and to appraise the context of clinical decision making, treatments chosen and the associated outcomes. The data retrieved from case reports will then be discussed in light of evidence gathered from human observational and experimental animal studies on compartment syndrome secondary to snakebite. The aim is to describe current treatment strategies and their underlying evidence base by providing a comprehensive overview of available literature on the subject. Shortcomings in evidence will be highlighted in order to map-out future research needs