In this paper, in order to achieve the resource utilization of metallurgical waste, this article studied the water resistance of magnesium oxysulfate cement coating using blast furnace slag powder and iron tailings powder as fillers, and characterized its hydration products using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results indicate that an appropriate amount of slag powder and iron tailings powder can make the internal structure of the coating more dense, effectively improve the softening coefficient, and enhance water resistance