Anchovy (Stolephorus sp) is a fish that usually consumed by most people in Indonesia. It is served as a famous dish in
Indonesian cuisine. It is a natural source of calcium, phosphor, and fluoride. In dentistry, anchovy had been studied
due to its bioactive content as bone stimulator and teeth development agent, topical fluoridative agent, and pulp capping agent. There are several methods in preparing anchovy extract that leads to different bioactive content. These
variations provide several roles as biomaterial in dentistry. The latest issue regarding anchovy was its hydroxyapatite
content. The previous study showed promising result and become a base of future exploration to obtain safe and
effective treatment in dentistry
