Guided Bone Regeneration (GBR) is a method treating a biomaterial that is located into the injured bone to prevent fibrous tissue from entering the injured bone area before the replacement bone grown completely, divided into polytetrafluoroethylene (e-PTFE), synthetic biodegradable polyester, and collagen membranes. The aim of this study is to present an evaluation of literature regarding the rule of novel Demineralized Dentin Material Membrane (DDMM) as GBR. Bone defect after surgical or trauma procedures can be corrected through several mechanisms, which depend on the level of restriction, the level of bone injury, and the physiological process. The use of guided bone regeneration aims to ensure perfect new bone growth, with the exact same shape as the original bone. The application procedure of DDMM as a GBR therapy for bone injury on craniomaxillofacial could be provide bone cells for bone regeneration and protects the bone regeneration process from non-osteogenic tissues
