Social media has become an important part of the daily lives of many individuals, especially among early adulthood. One of the popular social media platforms is TikTok. Majority TikTok users in Indonesia come from early adulthood, in age range from 18 to 25 years. One of the negative impacts of TikTok is the emergence of fear of missing out on information. Self-regulation is one of the important things in reducing the negative impact of Fear of Missing out (FoMo), this is because self-regulation has an important role in controlling an individual's ability to use social media This research aims to determine the relationship between self-regulation and FoMO among early adult users of the TikTok application. This research used quantitative methods with non-probability sampling, and accidental sampling technique and using a self-regulation scale and a FoMO scale which were then distributed via Google from involving a total of 139 respondents with the criteria for active early adult TikTok users and the age range of 18 to 25 years. The research results showed that there was a relationship between self-regulation ability and the level of FoMo in individuals(r = -0438 ; p = 0,00),, where the higher the level of self-regulation, the lower the level of FoMo felt by early adult individuals