Additional file 1 of Apoptotic extracellular vesicles derived from hypoxia-preconditioned mesenchymal stem cells within a modified gelatine hydrogel promote osteochondral regeneration by enhancing stem cell activity and regulating immunity

Abstract

Additional file 1. Fig.S1. The long-term destiny of transplanted stem cells in vivo. Fig.S2. Dio-labeled ApoEVs successfully loaded onto Gel/ECM scaffold at different magnification. Fig.S3. Vesicle structure loaded onto the scaffold under scanning electron microscope. Fig.S4. Results of Young's modulus of three groups of scaffolds. Table S1. Upregulated miRNA-related functions in H-ApoEVs. Table S2. The sequences of primer for the RT-qPCR. Table S3. International Cartilage Repair Society (ICRS) macroscopic evaluation guidelines. Table S4. Modified O’Driscoll score system