La presentazione illustra la strategia di Gestione dei dati della Ricerca adottata all'interno del progetto europeo Nymph

Biagi, Elena

Caldoni, Giulia

AMS Acta

NYMPHE Experience – managing data in Horizon projectElena Biagi, UNIBOGiulia Caldoni, UNIBOOctober 25th 2023 – Open Science Event25 October 2023The project at a glanceCall: HORIZON-CL6-2021-ZEROPOLLUTION-01 (Destination: Clean environment and zero pollution)Topic: HORIZON-CL6-2021-ZEROPOLLUTION-01-10 - Environmental services: improved bioremediation and revitalization strategies for soil, sediments and waterType of Action: Research and Innovation ActionStarting date: 1 January, 2023Duration: 48 monthsTotal cost: 5.702.902,80 €EU funding: 5.499.973,50 €Coordinator: Prof. Giulio Zanaroli, University of BolognaProject Officer: Dr. Lukas Varnas, European Research Executive AgencyNYMPHE consortiumObjectivesTo develop bioremediation / revitalization strategies based on bioremediation systems consisting of assemblies of multiple biologics,assess them from technical, environmental, economic and societal perspectives for the revitalization of polluted environments, andshowcase them at 4 real contaminated sites and 1 site for confined tests with genomically edited organisms, with the ambition of removing at least 90% of the main pollutants of the four polluted sites and improve their biodiversity status.Sites & target polluted matricesIGB site - Hyporheic zone (HZ) (Hoppegarten-Berlin, DE): River Erpe sediment and surface water contaminated with pharmaceuticalsCENVIS site – (Leopoldov, SK) site used as facility enabling the “confined use” of genomicallyedited biologics to remediate the contaminated matrices of ER, CHQ and IGB sitesER site - Industrial site (Ferrara, IT): groundwater (GW), aquifer sediments, and soil matrices contaminated with Petroleum Hydrocarbons(PHC) and chlorinated aliphatic hydrocarbons (CAH), heavy metals (HM) METFI site – Municipal WW (IMDEA Water, Alcala, ES): Municipal WW with pharmaceuticals(antibiotics) and microplastics (MPs)CHQ site - Agricultural field (Falassarna, GR): soil contaminated with microplastics (MPs)and pesticidesThe technical approachEnzymesMicroorganisms(bacteria, algae, fungi)Plants/holobiontsAnimals(clams, earthworms)Selection, isolation, characterization of the biologics for bioremediation of polluted sitesPlatforms for the improvement/enlargement of the biologicsNatural improvement of single tools (accelerated evolution)Engineered improvement(in silico, gene editing, synthetic biology)Strategies for Improvement  at system level(complementary pathways, microbiome control, community assembly)Reintroduction/tests in controlled environment for bioremediation/revitalizationSoil Sediment WaterSystems construction and modelling(microbiomes, rhizosphere, natural ecosystems)System 1 System 2 System 3 System nAssessmentTechnicalEnvironmentalEconomicalSocietalWP1WP2WP3WP4Research Data Management in Horizon Europe Projects- Manage data in line with FAIR principles- Establish and update a Data Management Plan (DMP)- “As open as possible, as closed as necessary”Tsoukala, V., Open Science in Horizon Europe (2021). https://es.slideshare.net/victsoukala/2021-05-oscytsoukala;  Communication, dissemination, open and visibility – article 17, annex 5, grant agreementThe Data Management Plan (DMP)The DMP is a MANDATORY deliverable for project funded by Horizon Europe programme. Is a roadmap to:​• Develop procedures early on for efficient and consistent research work, saving your time later on​.• Manage data to avoid problems like data duplication, loss, and security breaches.​• Make research materials visible and citable to maximize the impact of your work​.• Be aware of how you are fulfilling all your legal and ethical obligations​.Initial Worries & Challenges in DMP preparation- High number of partners, both research institutions and companies- WPs complex design in terms of data used and generated- Difficulty in translating complex and heterogenous scientificoutputs into organized datasets before actually obtainingthem- How to collect and harmonize information from partners - How to compromise between the requirement of disclosingthe content of datasets and the need of keeping data «hidden» before publicationWorries & Challenges in DMP preparation- High number of partners, both research institutions and companies- WPs complex design in terms of data used and generated- Difficulty in translating complex and heterogenous scientificoutputs into organized datasets before actually obtainingthem- How to collect and harmonize information from partners - How to compromise between the requirement of disclosingthe content of datasets and the need of keeping data «hidden» before publicationExample: WP2 - Systems design, assembly and modellingBiologicsperformance data from WP1 and WP3MetagenomicsMetagenomics dataMetagenomesand MAGsComputationalmethodsAssembly of biologicssystemsMicrobiomesmodellingMicrobiome digital twinsMicrobiome networksPerformance evaluation data• Systems composition and features• Measurments of parameters to assess performancesExample: WP4 - Testing and assessment of the remediation technologiesData, models and biologics from WP1-3SitespreparationSites features• Physicochemicalfeatures of eachevironmental matrix• Ecotoxicologicalfeatures of each siteBioremediationfield tests Assessment data• Measurments of parameters to assess performances• LCA, ECA, EA, RA data and outcomes• Societal assessment and stakeholder questionnaire dataBackground dataRegulatory background Existing bioremid technologySocietal background on bioremidPrivacy!UNIBO activities of coordination• Provide partners with a decision tree to understand what type of data each one will have to manage• Collect information from partners using a questionnaire with allnecessary questions to stimulate and guarantee a FAIR data management• Harmonize and integrate collected information to compile a first version of the DMP which includes the NYMPHE general approach to data management and a list of (for now) hypothetical datasets the project is going to produce…for the next 4 years, UNIBO will keep on updating and integratingthe information in the DMP and periodically provide an updatedversions.Define what kind of data a partner will have to manageDecisional tree to help researchers ask, and answer, questions they did not know they had.Starting from the fundamental bricks of the data lifecycle, integrates a series of questions aiming to encourage the researchers address some major attention points, encompassing issues including- privacy/ethics requirements- IPR legislation- Data storage and preservation- FAIR principles and Data depositUNIBO activities of coordination• Provide partners with a decision tree to understand what type of data each one will have to manage• Collect information from partners using a questionnaire with allnecessary questions to stimulate and guarantee a FAIR data management• Harmonize and integrate collected information to compile a first version of the DMP which includes the NYMPHE general approach to data management and a list of (for now) hypothetical datasets the project is going to produce…for the next 4 years, UNIBO will keep on updating and integratingthe information in the DMP and periodically provide an updatedversions.Partners questionnairePartners questionnaireUNIBO research groups filled in the questionnairebefore all other partners and provided the answersto them as an examplePartners questionnaireThe questionnaire approach had a very positive feedback from partnersUNIBO activities of coordination• Provide partners with a decision tree to understand what type of data each one will have to manage• Collect information from partners using a questionnaire with allnecessary questions to stimulate and guarantee a FAIR data management• Harmonize and integrate collected information to compile a first version of the DMP which includes the NYMPHE general approach to data management and a list of (for now) hypothetical datasets the project is going to produce…for the next 4 years, UNIBO will keep on updating and integratingthe information in the DMP and periodically provide an updatedversions.UNIBO activities of coordination• Provide partners with a decision tree to understand what type of data each one will have to manage• Collect information from partners using a questionnaire with allnecessary questions to stimulate and guarantee a FAIR data management• Harmonize and integrate collected information to compile a first version of the DMP which includes the NYMPHE general approach to data management and a list of (for now) hypothetical datasets the project is going to produce…for the next 4 years, UNIBO will keep on updating and integratingthe information in the DMP and periodically provide an updatedversions.…keeping the DMP updated- Keeping track of produced and published data within the consortium activity (thanks to partners meeting twice a year)- Reminding and helping partners who produced datasets in updating the infos in the DMP and making sure to deposit the data in appropriate repositoryFunded by the European Union. Views and opinions expressed are howeverthose of the author(s) only and do not necessarily reflect those of the EuropeanUnion or the European Research Executive Agency (REA). Neither the EuropeanUnion nor the granting authority can be held responsible for them.

NYMPHE Experience - managing data in Horizon project

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NYMPHE Experience - managing data in Horizon project

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