The competitiveness of the business today will depend on empowering hu-man intelligence and creativity, capturing and capitalizing on available infor-mation and knowledge for the total product and service lifecycle. To realize this beyond technical aspects, the collaborative work of multidisciplinary and inter-sectoral teams is constituted to develop an appropriate methodology of human-centred design (HCD) with advanced service innovation in indus-try 4.0. Based on the state-of-the-art analysis and industrial requirements, the methodology is tested with European industrial cases in various sectors to validate its implementation and benefits. This paper aims to provide the well-rounded collaborative framework to deliver the new HCD methodology
