Against
the background of the war in Ukraine, the COVID-19 pandemic has waned from public consciousness as the threat of the
virus to health is outweighed by safety concerns during the war. Pandemic restrictions in the European region are being
lifted despite low vaccination rates in Central and Eastern European countries and a lack of effective containment
strategies. However, Central and Eastern European countries are influenced most by the flow of refugees from
neighboring Ukraine where a triple health crisis occurs: an overloaded health system, an ongoing COVID-19 pandemic,
and the war. The aim: to review the progress regarding viral surveillance technologies that use genomics, digital, and
informational tools, to find the gap in the literature and formulate policy recommendations for continuing surveillance
in the context of permacrisis. Unstructured search was conducted through scientific (PubMed and Google Scholar
databases) and grey literature using the keywords. The paper highlights aspects of war-related problems of infectious
diseases control in Europe, new challenges in healthcare connected with COVID-19 pandemic and war in Ukraine and
provides discussion on the role of innovative surveillance systems in tackling infection outbreaks (with COVID-19 pandemic as an example). The paper overviews perspectives of the implementation of the discussed measures. Future
COVID-19 outbreaks and new variants are possible. Complex adaptive system models, new tools, and the next level of
health and digital intelligence are needed to provide timely and valuable insights. Combining lessons learned from the
COVID-19 pandemic, the threat of war, and the need for continuous outbreaks surveillance, new public health and digital
intelligence tools must be designed and implemented at regional, European, and global levels